Statistical analysis:
Descriptive statistics were used for analysing demographic, treatment
and disease characteristics. Quantitative variables are presented as its
mean (SD) and qualitative variables as frequency (%). Pulmonary
function test was classified as dichotomous variables-normal and
abnormal. The prevalence of pulmonary function abnormalities is
presented as frequency (%). The associated factors were also classified
as dichotomous variables. Age at evaluation, age at start of
chemotherapy and age at start of radiotherapy as ≤ 10 years and
>10years.Cumulative bleomycin dose was categorised as
≤80mg/m2 (1mg=1IU) and >80mg/m2. The associations of
categorical variables with abnormal pulmonary function was assessed
using chi-square/ Fisher’s exact test. A p-value less than 0.05 was
considered as statistically significant. Regression analysis and
multivariable analysis couldn’t be carried out due to less event rate in
our study sample. Analysis was done by stata14.