Artemisia
From the 868 metabolites that were detected in the Artemisia shoot samples, 451 (52%) metabolites were significantly different between at least two rhizobacteria treatments. In the PCA, the first two PCs explained 80% of the total variance (Figure 2b1 ). The first principal component explained more than 64% of the total variance and corresponds to metabolites that were either reduced or accumulated during the most effective partnership of the host with Pbg(Figure 2b1 and 2b2 cluster 1 ( reduced metabolites) and cluster 2 (induced metabolites)). Flavanones, flavonol glycosides, coumarins, benzoic acid derivatives, acylated polyamine, catechols, fatty acyl glycosides of mono- and disaccharides, dipeptide and terpene glycosides showed significant reductions uponPbg inoculation. Various other metabolites belonging to the compound classes hydroxycinnamoyl quinic acids and derivatives, organic acids, mono and diterpenoids, and iridoids showed a significant increase after root inoculation with Pbg . Treatment of Artemisia withPbg resulted in significant reduction in artemisinic acid while the relative levels of both dihydroartemisinin and artemisinic alcohol significantly increased. PC2 explained 16% of the total variance and corresponded to induced metabolites (cluster 3 ) in response toPf SS101 inoculation. Putative metabolite identification revealed that the amino acid arginine, fatty acyl glycoside blumenol glycoside and phenylpropanoid glycoside derivatives were induced in a PfSS101-specific manner.