Statements and Declarations:
Funding: The authors declare that no funds, grants, or other additional support (except for those indirect funding sources listed in acknowledgements) were received during the preparation of this research or manuscript.
Financial disclosures: The authors have no relevant financial or non-financial interests to disclose.
Author contributions: All authors contributed to the study conception and design. Material preparation, data collection and analyses were performed by Huong Meeks, Alison Fraser, and Devin Etcitty. The first draft of the manuscript was written by Susan Dalton and all authors commented on subsequent versions of the manuscript. All authors read and approved the final manuscript.
Ethics approval & Informed consent: Approval was obtained by the Institutional Review Board at the University of Utah (IRB# 00012636) and the Utah Resource for Genetic and Epidemiologic Research (UPDB# 00000441) before data collection or analyses were begun. This is a retrospective observational study of de-identified data and written informed consent of research participants was waived.