3.1.3. Fucoidan biosensor:
For the manufacture of the drug delivery system, Kurosaki et al. (2009) used fucoidan as a matrix material. Berger et al. (2010) has also used fucoidan and dextran sulfate as a biomaterial for HGF sensor coating. HGF has been attached specifically to sulfated polysaccharide fucoidan for the identification of hepatocyte growth factor in the serum-containing medium of a small bioreactor for culturing hepatocytes. Fucoidan coated HGF biosensor has shown highest sensitivity and low-cost alternative to the use of antibodies (Berger et al., 2010).