3.1.2.3. Chitosan-Based Electrochemical Immunosensors:
Electrochemical immunosensors based on Chitosan are created by immobilizing antibodies or antigens on the electrode surface of Chitosan. One of the advantages of chitosan is that the number of amino sites accessible for covalent protein attachment to chitosan materials may be varied across a large range merely by changing the degree of deacetylation of the variety. The fungal hepatocarcinogen aflatoxin B1 (Masoomi et al., 2013), botulisum neurotoxin A (Afkhami et al. 2017), diarrhea triggering bacteria Shigella flexneri, Ochratoxin A, hepatitis B biomarkers, cancers and iron content of blood (Liang et al., 2014) are detected and monitored by using electrochemical immunosensors.
Figure 3 : DNA immobilization on electrode surfaces using chitosan.