Case 2
A 70-year-old woman attended our dermatology clinic with diffuse skin
eruptions of one month duration. She complained of a progressive
maculopapular rash beginning from the arms, and extending to all the
body surface, with gradual stiffness of the lesions. She acknowledged
that the condition started 2 days after getting the first dose of
AstraZeneca SARS-CoV-2 vaccine. Physical examination revealed multiple
sclerotic skin eruptions all over the body including intertriginous
areas (figure 2). Deep skin biopsy revealed scledermoid changes. Her
polymerase chain reaction (PCR) test for SARS-CoV-2 was reported
negative. Other laboratory tests including complete rheumatology panel
were normal. Tumor markers and other assessments for malignancies also
did not reveal an underlying cancer. Our patient refused to undergo
phototherapy, so we started her on methotrexate and topical
corticosteroids and are waiting to see the response.