Giant Tumor of the perineal region
Key clinical message: Giant condyloma acuminatum, also known
as, Buschke-Lowenstein tumour is a very rare, sexually transmitted
disease. It is a slow-growing, destructive lesion that affects the
anogenital region. The HPV has been identified as an important
contributory factor in the development of this tumor.
Key words: Dermatology, oncology, Giant condyloma acuminatum ,
HPV.
A 48-year old man presented with a giant lesion of the perineal region
which appeared 10 years before and gradually increased in size. Clinical
examination revealed a lobulated, exophytic, non-painful, non-bleeding,
cauliflower-shaped lesion on the penis and the scrotum, measuring
approximately 8 x 7 cm suggestive of a giant condyloma acuminatum
(Figure 1). There were no enlarged inguinal nodes. Magnetic resonance
imaging of the pelvis and the abdomen revealed no regional lymph node
involvement or evidence of distant metastasis. A skin biopsy confirmed
the diagnosis of papillary condyloma acuminatum secondary to human
papillomavirus (HPV). Radical excision of the entire lesion showed no
signs of invasion. Blood tests for detecting Human Immunodeficiency
Virus (HIV), Hepatitis B Virus (HBV), Hepatitis C virus (HCV) and
syphilis were negative. Giant condyloma acuminatum, also known as,
Buschke-Lowenstein tumour is a very rare, sexually transmitted
disease.1,2 It is a slow-growing, expansive,
cauliflower-like, destructive lesion that affects the anogenital region.1,2 The HPV has been identified as an important
contributory factor in the development of this tumor.1,2