Genome wide Tajima’s D is associated with bacterial evolutionary
history
Phylogenetic analyses of all SGBs in combination with intraspecific
scans for balancing selection revealed that genome-wide estimates of
Tajima’s D were associated with bacterial phylogenetic history (Figure
1) (phylosig p -value = 1.63e-06). In addition, we observed
significant differences among the mean genome-wide Tajima’s D among
bacterial genera. Figure 1B presents these genome-wide Tajima’s D
estimates for all bacterial genera represented by >6 SGBs.Bifidobacterium and Faecalibacterium displayed the most
negative genome-wide Tajima’s D, whereas Bacteroides displayed
the highest. After correction for multiple testing, significant
differences in genome-wide Tajima’s D at the p < 0.001
significance threshold were observed between Bifidobacterium andBacteroides and between Faecalibacterium andBacteroides . A table of false-discovery rate corrected p-values
generated from all pairwise comparisons of genome-wide Tajima’s D is
presented in Table S2.