Genome wide Tajima’s D is associated with bacterial evolutionary history
Phylogenetic analyses of all SGBs in combination with intraspecific scans for balancing selection revealed that genome-wide estimates of Tajima’s D were associated with bacterial phylogenetic history (Figure 1) (phylosig p -value = 1.63e-06). In addition, we observed significant differences among the mean genome-wide Tajima’s D among bacterial genera. Figure 1B presents these genome-wide Tajima’s D estimates for all bacterial genera represented by >6 SGBs.Bifidobacterium and Faecalibacterium displayed the most negative genome-wide Tajima’s D, whereas Bacteroides displayed the highest. After correction for multiple testing, significant differences in genome-wide Tajima’s D at the p < 0.001 significance threshold were observed between Bifidobacterium andBacteroides and between Faecalibacterium andBacteroides . A table of false-discovery rate corrected p-values generated from all pairwise comparisons of genome-wide Tajima’s D is presented in Table S2.