Experimental protocol
The design, analysis and reporting of the research were carried out
according to the ARRIVE guidelines (Percie du Sert et al., 2020). The
animals were randomly divided into 6-10 mice per group.
Randomized treatments were administered according to the method of equal
blocks to assess simultaneously the effect of the different treatments
and to avoid unverifiable and time-variable environmental influences.
All experiments were performed in a quiet room by the same blinded
experimenter.