Disease severity in NAFLD patients with normal or elevated intestinal permeability
Next, we analyzed disease severity in NAFLD patients with normal or elevated intestinal permeability. NAFLD patients with elevated intestinal permeability (D-lactate: 19.00 [16.48–23.23] U/L) had significantly higher levels of liver test parameters ALT, AST, GGT, TBIL, and IBIL (all PĖ‚0.05); higher levels of the liver ultrasonographic parameter, FAP (P=0.001); higher levels of TG (P=0.023) and an elevated HOMA-IR value (P=0.020) among metabolic parameters; and a higher level of the intestinal parameter, DAO (P=0.025), than those with normal intestinal permeability (D-lactate, 9.35 [6.47–12.40] U/L) (Table 2 ).