Disease severity in NAFLD patients with normal or elevated
intestinal permeability
Next, we analyzed disease severity in NAFLD patients with normal or
elevated intestinal permeability. NAFLD patients with elevated
intestinal permeability (D-lactate: 19.00 [16.48ā23.23] U/L) had
significantly higher levels of liver test parameters ALT, AST, GGT,
TBIL, and IBIL (all PĖ0.05); higher levels of the liver ultrasonographic
parameter, FAP (P=0.001); higher levels of TG (P=0.023) and an elevated
HOMA-IR value (P=0.020) among metabolic parameters; and a higher level
of the intestinal parameter, DAO (P=0.025), than those with normal
intestinal permeability (D-lactate, 9.35 [6.47ā12.40] U/L)
(Table 2 ).