Figure 2 Frequentist sampling distribution and Bayesian posterior distribution of the geometric means ratio (GMR) generated in the matched/adjusted comparison of total exposure (AUCτ,ss) in variant allele carriers and wild type controls. Dotted vertical lines indicate GMR=1.00 (“no effect”) and GMR=1.20 – depicted are probabilities of GMRs >1.0 and >1.20.