Results
136 patients, whose TTE and RHC data were analyzed were included in the study. The mean age of the patients included in the study was 57.67 ± 13.36 and 59 (43.4%) patients were male. General characteristics, clinical features, TTE and RHC findings of the patients are shown in Table-1. IVCDmax, IVCDmin and IVCCI values were 18.5 mm, 11.14 mm, 42.41%, respectively. CSDmax, CSDmin and CSCI values were 11.46 mm, 6.92 mm, 40.58%, respectively.
The average RAP was measured as 9.84 ± 5.39 mmHg. In 57 patients, invasively measured RAP was ≥10 mmHg, in 79 patients RAP was <10 mmHg. In the group with RAP ≥10 mmHg, the diameters of IVC and CS and their diameters indexed to BSA were higher than the group with RAP <10 mmHg. In addition, in the group with RAP≥10 mmHg, IVCCI and CSCI and collapse indices indexed to BSA were lower. All parameters were statistically significant (p <0.001)(Table-2).
CS and IVC parameters of the patients included in the study were compared with each other as well as with invasively measured RAP values and the correlation between them was evaluated. CSDmax and CSDmax/BSA were compared with IVCDmax and IVCDmax/BSA and a moderate relationship was found between them(r: 0.554 p <0.001; r: 0.597 p <0.001, respectively). CSDmin, CSDmin/BSA and CSCI were compared with IVCDmin, IVCDmin/BSA and IVCCI and a high level of significant relationship was found between them(r: 0.712 p <0.001; r: 0.717 p < 0.001; r: 0.608 p <0.001 respetively)(Figure-2).
Invasively measured RAP was compared with CSDmax and CSDmax/BSA and a moderate significant correlation was found between them (r: 0.478 p <0.001; r: 0.484 p <0.001, respectively). Invasively measured RAP was compared with CSDmin, CSDmin/BSA and CSCI and a high level of significant relationship was found between them(r: 0.711 p <0.001; r: 0.691 p <0.001; r: -0.674 p <0.001, respectively)(Figure-3).
There was a moderately significant relationship between RAP and IVCDmax and IVCDmax/BSA(r: 0.615 p <0.001, r: 0.518 p <0.001). Finally, there was a high level of significant correlation between RAP and IVCDmin, IVCDmin/BSA and IVCCI (r: 0.705 p <0.001; r: 0.659 p, <0.001; r:-0.683 p <0.001respectively)(Figure-4).
According to ROC analysis; for predicting RAP≥10 mmHg, optimal cut-off value of IVCDmax was found to be 19.6 mm (sensitivity, 63.2%; specificity, 87.3%), optimal cut-off value of IVCDmax/BSA was found to be 10,6 mm/m² (sensitivity, %64,9; specificity,%81), optimal cut-off value of IVCDmin was found to be 10 mm (sensitivity, %73,7; specificity,%82,3), optimal cut-off value of IVCDmin/BSA was found to be 5,8 mm/m² (sensitivity, %68,4; specificity, %87,3), optimal cut-off value of IVCCI was found to be 46,1 (sensitivity, %75,4; specificity, %79,7), optimal cut-off value of CSDmax was found to be 11 mm (sensitivity, %64,9; specificity, %77,3), optimal cut-off value of CSDmax/BSA was found to be 5,8 mm/m² (sensitivity, %77,1; specificity,%58,2), optimal cut-off value of CSDmin was found to be 6,1 mm (sensitivity, %84,2; specificity, %77,2), optimal cut-off value of CSDmin/BSA was found to be 3,6 mm/m² (sensitivity, %78,9; specificity,%79,7), optimal cut-off value of CSCI was found to be 39,2 (sensitivity, %75,4; specificity, %88,6). All parameters were statistically significant (p <0.001)(Table-3).