RESULTS
The groups were found as similar (p>0.05) in regards of demographical variables (age, gender, smoking) and markedly higher abnormal FMD responses rates detected in primary RP patient group (p= 0.000). The comparison of demographical, clinical (FMD) and laboratory variables between control and pRP patients was demonstrated in Table 1.
Serum hemoglobin, platelet, creatinine, ALT, D-Dimer, FAR, NLR, albumin, DDAR values were found as similar between groups (p>0.05). Slightly higher AST values (p= 0.027) were detected in pRP group (25.60±9.77 IU/L) when compare with healthy subjects (21.20±5.14 IU/L). Serum WBC, MPV, fibrinogen and MCP-1 values were significantly higher in pRP group (Table 1) when compare with healthy control group (p<0.05).
Higher MCP-1 values (Figure 2) were detected in participants with abnormal FMD response (p=0.001). The significant correlation was detected between abnormal FMD response and MCP-1 levels (R: 0.308, R2: 0.095, p: 0.044). Additionally, the low level of relationship was found between FMD response and MPV, MCP-1 and fibrinogen values (Table 2).