Clinical correlations with the Enzian
Previous studies (4) (8) reported the correlations between the Enzian and pain symptoms in deep endometriosis. Haas et al reported no combinations of compartments, but choose to report the compartment with the highest severity: for example, A1B0C3 would become a solitary C in the analysis. In real life, endometriosis does not respect the compartment boundaries of the Enzian classification and therefore it is difficult to translate these findings directly to the clinical symptoms. Montanari et al performed a similar analysis with a more robust cohort. Nevertheless, both studies failed to study the solitary compartments and combinations of compartments in correlation to pain symptoms.
Therefore, our research questions that we addressed are: 1) Which compartment is responsible for the severity of the different types of pain? 2) Does pain increase with an increase in compartment involvement. 3) Do specific clinical symptoms correlate with the scoring in the Enzian.
The primary aim of our study was to find a correlation of the Enzian score with pain symptoms in DE. Secondly, we wished to determine whether a correlation exists between the extent of the disease and the reported intensity of pain (regarding solitary compartments and combinations of compartments).