Figure 1. Epitope mapping difference plot between PRN and PRN/mAb (1-6, 3-3, 3-5, 3-16, 3-21, and 3-4) complexes. Red dashed lines represent the 1.1 Da threshold and the blue dashed lines represent 3σ. The epitopes are highlighted in coloured stars according to the mAbs tested and are also coded in the three-dimensional structure with the corresponding colours.