Figure 4: Structure-activity relationships of MQ1. (A)Affinities ratios of MQ1 variants. **: p value=]0.01; 0.001]. ***: p value < 0.001. N-ter: MQ1 without the four first residues RPSF. N&C-ter: MQ1 without the four first residues RPSF without the two last residues GV and with the terminal cysteine residue being amidated. (B) Front and back sticky representation of tested MQ1 positions (PDB: 5m4v). Variants which influence (red) or not (green) on MQ1 affinity for hV2R are shown.