Figure 4: Structure-activity relationships of MQ1. (A)Affinities ratios of MQ1 variants. **: p value=]0.01; 0.001]. ***: p
value < 0.001. N-ter: MQ1
without the four first residues RPSF. N&C-ter: MQ1 without the four
first residues RPSF without the two last residues GV and with the
terminal cysteine residue being amidated. (B) Front and back
sticky representation of tested MQ1 positions (PDB: 5m4v). Variants
which influence (red) or not (green) on MQ1 affinity for hV2R are shown.