Conclusion
The findings of the present meta-analysis do not support a significant increase of serum LDH in hypertensive disorders of pregnancy with the exception of patients with that develop severe preeclampsia. Even in this latter group, however, the actual diagnostic accuracy of the enzyme seems to be limited by the scarce available evidence. Its predictive accuracy in determining adverse maternal and neonatal outcomes is extremely limited and is mainly based in pregnant women that develop hemolysis. Future research should expand in this field, rather than assessing differences in serum LDH values among the various subgroups of hypertensive disorders of pregnancy.