Adhesion Barriers
A total of 13 adhesion barriers and 2,928 patients were identified
(2,928 received barrier; 522 received barrier and re-operation). The
names and composition of these barriers as well as their study data are
outlined in Table 2. The adhesion barriers assessed were
Polytetrafluoroethylene (PTFE) (n=13 studies, 67% of patients),
Seprafilm (n=3, 14%), COSEAL (n=2, 3%), REPEL-CV (n=2, 3%),
Glutaraldehyde-Preserved Equine Patch (n=1, 7%), Silicone Rubber (n=1,
3%), Cova CARD (n=1, 1%), Polyglycolic Acid Mesh (n=1, 1%), SprayGel
(n=1, 0.3%), Polyisoprene Blue Band Strips (n=1, 0.3%), and Porcine
and Polyester Gelatin Sheet (n=1, 0.2%). Two barrier combinations were
also identified: PTFE + SprayGel (n=1, 0.3%) and PTFE + Seprafilm (n=1,
0.1%). The mean number of studies per barrier was 2.2 with a mean of
225 barrier patients and 23 barrier patients with re-operation.
Excluding PTFE, the mean number of studies per barrier was 1.3 with a
mean of 81 barrier patients and 24 barrier patients with re-operation.
The mean study year was 2003 with a range from 1981 (Silicone Rubber) to
2015 (Seprafilm).