Running title: Vicilin leader sequences contribute to cross-reactivity
Jacqueline B. Nesbit*1, Alexander C.Y. Foo*2, Stephen A.Y. Gipson1, Pierre Bushel2, Eugene F. DeRose2, Hsiaopo Cheng1, Catherine H. Schein3, Suzanne S. Teuber4, Barry K. Hurlburt1, Geoffrey A. Mueller†2, Soheila J. Maleki†1
1- USDA-ARS
2- National Institute of Environmental Health Sciences
3- Department of Biochemistry and Molecular Biology, Institute for Human Infections and Immunity, University of Texas Medical Branch, 301 University Blvd., Galveston TX 77555
4- University of California Davis School of Medicine
* Denotes equal contributions
† Corresponding authors:
Soheila.Maleki@usda.gov
1100 Robert E Lee Blvd.
New Orleans, LA 70124
504-286-4590
Geoffrey.Mueller@nih.gov
111 T.W. Alexander Dr. MD-MR01
Research Triangle Park, NC 27709
Authors contributions : JBN Performed the microarray analysis and wrote a significant part of the manuscript; ACYF performed a majority of the structural experiments and wrote a significant part of the manuscript; EFD and GAM assisted with structural studies. SAYG performed the statistical analysis with guidance from PB. BKH, HC designed and performed the microarray experiments; CHS performed the PD computational work; SJM and GAM co-directed the study design and implementation and, helped prepare figures and manuscript.