Table 3: Incidence and relative risk of developing GDM/DM at the second trimester by fatty liver grade
Of the rest, 348 pregnant women were assessed at the end of the second trimester. Two cases of DM in pregnancy and 11 GDM cases were detected among previously normoglycaemic women. The incidence of DIP/GDM of FLG I, II and III in the second trimester was 11.0, 43.9 and 162.2 per 1000 pregnancies respectively. The unadjusted relative risk of developing DIP/GDM in the second trimester compared to FLG 0 was 3.8 (95% CI 0.79-19.4) and 12.5 (95% CI 2.6-60.0) for FLG I and FLG II, respectively. The unconfounded effect of FL on developing GDM/DIP was assessed using a binary logistic regression model with waist-to-hip ratio, age, parity, FL grades, family history of diabetes, female education, and BMI as probable confounders (Table 4). Only the FL grade II was emerged as a significant risk factor for developing DIP/GDM with a OR of 12.3.