Predictors of mortality
To assess the predictors of
mortality, we performed bivariate, and multivariate COX regression
analysis of independent variables and results are mentioned in Table 3.
On Bivariate analysis, factors associated with increased mortality were
neonatal complications, BMI for age z score at the time of diagnosis,
FEV1/FVC, FEF25-75, recurrent pneumonia, total IgE level (IU/ml ), HCO3
level at the time of admission (mEq/l), SK severity score at the time of
admission, and age at the time of diagnosis.
On multivariable Cox regression analysis, significant factors associated
with mortality included the presence of neonatal complications, low
z-scores for BMI at the time of diagnosis, low FEV1/FVC and low FEF25-75
at the time of diagnosis (Table 3).