Dear Dr Cremers,

Providing children, parents and health care providers with high quality drug safety information and managing treatment related risks requires an understanding of the specifics of paediatric pharmacovigilance and risk management in clinical trials and clinical practice.

The conect4children (c4c) has recently formed in order to support researchers contacting the c4c network for the conduct of paediatric trials. In this context we have written a small review on key aspects concerning paediatric pharmacovigilance with a focus on providing practical advice in a white paper for the c4c themed issue.

We are looking forward to your feedback.

Thank you.

Sincerely,

Beate Aurich

MD, MRCPCH

Paediatric pharmacovigilance and pharmacoepidemiology physician

Project Leader Paediatric Clinical Pharmacology

Saint-Louis Hospital

1 Avenue Claude Vellefaux

75010 Paris, France