2.1. Study Design
This research is a cross-sectional study.
2.2. Variables
Data6,7 showing the sum of A1AT PI*SZ and PI*ZZ
genotypes numbers of countries in Europe and America were compared with
the case and mortality numbers related to the COVID-19 pandemic as
published by Worldometer13 on March 30, 2021 (Table 1,
Table 2).
Since the A1AT PI*SZ and PI*ZZ data of countries other than Europe and
America are insufficient and the numbers of COVID-19 pandemic cases and
deaths in the Worldometer database were not considered reliable for each
country, only the data of these two regions have been analyzed. In
addition, Iceland from the European continent was excluded from the
study due to the lack of data, and Russia was excluded because of the
low reliability of the data as well as its geographical location in the
Asian continent.