Figure 4: Secondary chemical shift analysis extrapolated for theD0 state of
mHIV-1-PR1-95 . For each residue, the
chemical shifts under different experimental conditions were
extrapolated to zero denaturant. Here we report the average of these
extrapolations. The secondary chemical shifts were calculated by the use
of the intrinsic random coil reference. The error bars indicate the
total error of the procedure. Different nuclei were monitored (a)
Cα, (b) C ’, (c) N and (d)
HN. The secondary structure of
mHIV-1-PR1-95 is shown at the top.