Introduction:
Primary bone diffuse large B-cell lymphoma (PB-DLBCL) is a destructive primary extranodal lymphoma that accounts for 55.7 % of all primary bone lymphomas. (1)
Patients are clinically presented with bone pain that is not relieved by rest, soft tissue swelling, palpable mass, pathologic fracture, joint contracture, cord compression, and systemic symptoms such as fever, unintentional weight loss, and night sweats. (2)
The common primary site of bone involvement is the axial skeleton rather than the appendicular skeleton (63 versus 37 percent ). (3)
The diagnosis of (PB-DLBCL) is based on both imaging and histopathologic findings. tissue samples can be taken either percutaneously or via open biopsy.
few primary bone lymphoma cases have been reported in the literature. These cases are usually misdiagnosed, particularly with osteomyelitis. the symptoms often persist for many months before the patient seeks appropriate medical care(4)
herein, we describe a 34-year-old young man with persistent bone pain whose core needle biopsies were consistent with osteomyelitis, however, his open biopsy revealed PB-DLBCL to be the underlying cause.