Conclusion:
Cor-Knot device is currently being used for intracardiac applications such as implanting pericardial valve in minimally-invasive mitral valve replacement. We have now utilized the Cor-Knot automated suture fastening system to close small caliber sites in aorta, such as root vents, instead of traditional suturing technique for over 4 years without any suture site complications. In this report we have demonstrated the safety of using this suture fastener system on large bore aortic cannulation sites also. One of the benefits of using this device is that it allows direct visualization of the site as the sutures are being tightened. This should be considered for direct aortic cannulation not only in minimally invasive but also open surgery where this provides controlled deployment under direct vision, rather than manual suturing with “feeling” the tightness of the knot by the surgeon’s hands.