FIGURE 6 Interspecific distribution of benign (BEN), deleterious (DEL), and loss of function (LOF) mutation alleles and genotypes for S. tergeminus (STER; blue circles ) andS. catenatus (SCAT; red circles ) individuals across 3,800 conserved genes. Analyses based on Species level mutations (see Methods). (a) Mean number of counts for each allele class. Mean relative proportions of (b) alleles, (c) homozygotes, and (d) heterozygotes for each class site are also presented.(e) Boxplots represent the distribution of mean PROVEAN scores across alleles present in homozygous (HOM) and heterozygous (HET) state (LOF alleles were given a default value of −12). ***P < 0.001; **P < 0.01; *P < 0.05; ns = nonsignificant