Background:
Perinuclear anti-neutrophil cytoplasmic antibodies (P-ANCA), a subset of
ANCA, are associated with a multisystem vasculitis affecting small blood
vessels in the body. A handful of adult patients who developed
vasculitis post-COVID-19 infection have been reported. Although COVID-19
infection has been shown to drive an exaggerated immune response in the
pediatric population, such as MIS-C (multisystem inflammatory syndrome
in children), only one case of vasculitis following COVID-19 infection
has been reported previously in children.