REFERENCES
  1. Zhu N, Zhang D, Wang W, Li X, Yang B, Song J, Zhao X, et al. A novel coronavirus from patients with pneumonia in China, 2019. N Engl J Med. 2020;382(8):727-733.
  2. Riphagen S, Gomez X, Gonzalez-Martinez C, Wilkinson N, Theocharis P. Hyperinflammatory shock in children during COVID-19 pandemic. Lancet. 2020;395(10237):1607-1608.
  3. Verdoni L, Mazza A, Gervasoni A, Martelli L, Ruggeri M, Ciuffreda M, Bonanomi E, et al. An outbreak of severe Kawasaki-like disease at the Italian epicentre of the SARS-CoV-2 epidemic: an observational cohort study. Lancet. 2020;395(10239):1771-1778.
  4. Satturwar S, Fowkes M, Farver C, Wilson AM, Eccher A, Girolami I et al. Postmortem Findings Associated With SARS-CoV-2: Systematic Review and Meta-analysis. Am J Surg Pathol 2021 Jan 20. doi:10.1097/PAS.0000000000001650. Online ahead of print.
  5. Harris CK, Hung YP, Nielsen GP, Stone JR, Ferry JA. Bone Marrow and Peripheral Blood Findings in Patients Infected by SARS-CoV-2. Am J Clin Pathol. 2021 Jan 27:aqaa274. doi: 10.1093/ajcp/aqaa274. Online ahead of print.
  6. Prilutskiy A, Kritselis M, Shevtsov A, Yambayev I, Vadlamudi C, Zhao Q, Kataria Y, Sarosiek SR, Lerner A, Sloan JM, Quillen K, Burks EJ. SARS-CoV-2 Infection-Associated Hemophagocytic Lymphohistiocytosis.Am J Clin Pathol. 2020 Sep 8;154(4):466-474. doi: 10.1093/ajcp/aqaa124.
  7. Lorenz G, Moog P, Bachmann Q, La Rosee P, Schneider H, Schlegl M, Spinner C, Heemann U,  SchmidRM, Algül H, Lahmer T ,  W SchmadererC. Cytokine release syndrome is not usually caused by secondary hemophagocytic lymphohistiocytosis in a cohort of 19 critically ill COVID-19 patients. Sci Rep2020 Oct 26;10(1):18277. doi: 10.1038/s41598-020-75260-w.
  8. Wood H, Jones JR, Hui K, Mare T, Pirani T, Galloway J, Metaxa V, Benjamin R, Rutherford A, Cain S, Kulasekararaj AG. Secondary HLH is uncommon in severe COVID-19. Br J Haematol. 2020 Sep;190(5):e283-e285. doi: 10.1111/bjh.16934. Epub 2020 Aug 10.
  9. Garcia-Pavon S, Yamazaki-Nakashimada MA, Baez M, Borjas-Aguilar KL, Murata C: Kawasaki disease complicated with macrophage activation syndrome: a systematic review. J Pediatr Hematol Oncol. 2017, 39:445-451.
  10. Ulloa-Gutierrez R, Alphanse MP, Dharanja A, Yeung RS, Kawasaki disease associated cytokine storm syndrome. Cytokine Storm Syndrome, Springer 2019, 393.
  11. Fardet L,   Galicier L,  Lambotte O,  Marzac C,  Aumont C,  Chahwan D, Coppo P,  Hejblum G. Development and validation of the HScore, a score for the diagnosis of reactive hemophagocytic syndrome. Arthritis Rheumatol 2014 Sep;66(9):2613-20. doi: 10.1002/art.38690.
  12. Sag, E., Keskin, A., Atalay, E., Demir, S., Cuceoglu, M. K., Akca, U. K., … Ozen, S. (2020). Performances of the “MS-score” And “HScore” in the diagnosis of macrophage activation syndrome in systemic juvenile idiopathic arthritis patients. Rheumatology International.  doi:10.1007/s00296-020-04750-x
  13. Clark, K. E. N., Nevin, W. D., Mahungu, T., Lachmann, H., & Singh, A. (2020). Assessment of the Haemophagocytic lymphohistiocytosis HScore in patients with COVID-19. Clinical Infectious Diseases. doi:10.1093/cid/ciaa1463
  14. Lee PY, Day-Lewis M, Henderson LA, Friedman KG, Lo J, Roberts JE, Lo MS, Platt CD, Chou J, Hoyt KJ, Baker AL, Banzon TM, Chang MH, Cohen E, de Ferranti SD, Dionne A, Habiballah S, Halyabar O, Hausmann JS, Hazen MM, Janssen E, Meidan E, Nelson RW, Nguyen AA, Sundel RP, Dedeoglu F, Nigrovic PA, Newburger JW, Son MBF. Distinct clinical and immunological features of SARS-CoV-2-induced multisystem inflammatory syndrome in children. J Clin Invest. 2020 Nov 2;130(11):5942-5950. doi: 10.1172/JCI141113.
  15. Hamada H, Suzuki H, Onuichi Y, Ebata R, Terai M, Fuse S et al. Efficacy of primary treatment with immunoglobulin plus ciclosporin for prevention of coronary artery abnormalities in patients with Kawasaki disease predicted to be at increased risk of non-response to intravenous immunoglobulin (KAICA): a randomised controlled, open-label, blinded-endpoints, phase 3 trial. Lancet 2019 Mar 16;393(10176):1128-1137. doi: 10.1016/S0140-6736(18)32003-8.
  16. Patel M, Dominguez E, Sacher D, Desai P, Chandar A, Bromberg M et al. Etoposide as Salvage Therapy for Cytokine Storm Due to Coronavirus Disease 2019. Chest 2021 Jan;159(1):e7-e11. doi: 10.1016/j.chest.2020.09.077.
  17. Yeung RS, Ferguson PJ. Is myltisystem inflammatory syndrome in children on the Kawasaki syndrome spectrum?. The Journal of Clinical Investigation. 2020;130(11):5681-5684. doi: 10.1172/jc1141714.