INTRODUCTION
Anastomotic leak (AL) after intestinal surgery has a dramatical impact on patient’s outcome regarding its high morbidity (35%) and variable mortality (4-22%)1,2.Although early diagnosis and immediate intervention improves the prognosis, in many patients, due to non-specific symptoms and indeterminate radiologic imaging, clinical diagnosis of AL may delay untill 6-12 days after surgery3.
Previous studies have shown that inflammatory biomarkers like procalcitonin (PCT) and C-reactive protein (CRP) may be useful in the early diagnosis of AL after major surgeries4. But, up to now, no studies evaluating the role of these markers in the early detection of AL after gyne-oncological operations have been found in the literature.
In the present study, we aimed to analyze the serum markers for the early diagnosis of AL after the gyne-oncological operations.