Animals
Male C57BL/6J mice, 5-6 weeks old, were purchased from the Beijing Vital River Laboratory Animal Technology Co., Ltd. (Beijing, China). Mice were housed in pathogen-free conditions and fed with food and water ad libitum. The study was approved by the local ethics committee of The First Hospital of Jilin University, Changchun of China and all experimental procedures complied with the regulations for the management of laboratory animals in the Jilin Province (Ethical approval number: 2017-216).
Reagents
The neuritogenic P0 peptide 180-199 was synthesized by GenScript (USA). BAY11-7082 was purchased from Beyotime (China). Antibodies against NF-κB p65 and NF-κB phosphorylated p65 were purchased from Cell Signaling Technology (USA).