Increasing the efficiency of hyperthermic intraperitoneal
chemotherapy (HIPEC) by a combination with a photosensitive drug in
pediatric rhabdomyosarcoma
Benedikt R. Wagner1*,
+, Anna L. Adamus1+, Laura
Hempfling1, Reza Vahdad1, Antje
Haap-Hoff2, Benedikt Heinrich3,
Olalla Vázquez3,4, Paul Jank5,
Carsten Denkert5, Guido Seitz1
1Department of Pediatric Surgery,
University Hospital Marburg, Baldingerstrasse,
35033 Marburg, Germany.
2 KARL STORZ SE
& Co. KG, Dr.-Karl-Storz-Strasse 34, 78532 Tuttlingen, Germany.
3 Department of Chemical Biology, Philipps-University
Marburg, Hans-Meerwein-
Strasse 4, 35043 Marburg, Germany.4 Center for Synthetic Microbiology (SYNMIKRO),
Karl-von-Frisch-Strasse 14, 35032
Marburg, Germany.
5 Department of Pathology, University Hospital
Marburg, Baldingerstrasse, 35043
Marburg, Germany.
+ Dres. Wagner and Adamus contributed equally to the first authorship of
this paper.
* Corresponding author:
Benedikt Wagner, Department of Pediatric Surgery, University Hospital
Marburg,
Baldingerstrasse, 35033 Marburg, Germany.
Tel.: +49 (0) 6421/58-66226
Email: bwagner@med.uni-marburg.de
This paper has been presented at the 53rd Annual
Congress of the International Society of Paediatric Oncology 2021 and
was the winning abstract of the Jack Plaschkes Price of the
International Society of Paediatric Surgical Oncology (IPSO).
Word Count for:
a) Abstract: 247
b) Main Text: 3575
The number of:
a) Tables: 1
b) Figures: 5
c) Supporting Information files: 1
Running title
Combination of Hypericin PDT with
HIPEC