General characteristics of the population
One hundred and seventy-nine (n=179) children with FPIES were included. The female to male ratio was 0.88 (53.1% of boys) (Table I). The median age at the onset of the first symptoms of FPIES was 5.8 months (3.0-8.0) and was younger for CM than for solid foods (Table II). Personal history of atopic disease was found in 67/165 children (40.6%), including 47 children (70.1%) with atopic dermatitis, and 22 children with asthma (32.8%). A total of 113/168 children (67.3%) reported at least one first-degree related family member with a history of atopic diseases (Table I).