Confirmed N=151 Presumptive N=41
p
Acute FPIES 112 (74.2%) 33 (80.5%) 0.5
Chronic FPIES 39 (25.8%) 8 (19.5%) 0.5
Sex ratio (male/female) (% boys) 76/75 (50.3%) 20/21 (48.8%) 1.0
Atopic history Personal Paternal Maternal Siblings 52/140 (37.1%) 44/145 (30.3%) 68/145 (46.9%) 17/33 (51.5%) 20/37 (54.1%) 16/36 (44.4%) 19/36 (52.8%) 4/11 (36.4%) 0.09 0.1 0.6 0.5
Age at first symptoms (months) 5.0 (3.0-8.0) 6.0 (3.7-10.5) 0.049
Main culprit food Cow’s milk Hen’s egg Fish Other foods 93 (61.6%) 20 (13.2%) 13 (8.6%) 25 (16.6%) 15 (36.6%) 9 (22.0%) 8 (19.5%) 9 (22.0%) 0.005 0.2 0.9 0.5
Minor Criteria (acute FPIES) (mean) Recurrent vomiting after same food Lethargy Pallor Emergency department visit Diarrhea Intravenous fluid support Vomiting after different food Hypotension Hypothermia 3.7 per FPIES 98/112 (87.5%) 90/112 (80.4%) 71/112 (63.4%) 49/112 (43.8%) 41/112 (36.6%) 39/112 (34.8%) 25/112 (22.3%) 6/87 (6.9%) 0 2 per FPIES 25/33 (75.8%) 18/33 (54.5%) 6/32 (18.2%) 6/33 (18.2%) 7/33 (21.2%) 1/31 (3.2%) 3/33 (9.1%) 0/23 0 <0.001 0.1 0.006 <0.001 0.008 0.1 <0.001 0.1 0.3 -
Positive IgE 20/142 (14.1%) 8/38 (21.1%) 0.3
Severe form 13 (8.6%) 0 0.07
Age at first OFC 2.0 (1.4-2.9) 2.3 (0.8-2.9) 0.3
Age at tolerance 2.1 (1.7-3.0) 2.5 (1.6-2.9) 0.7
Number of tolerant patients 114 (75.5%) 37 (90.2%) 0.05