Acute FPIES |
112 (74.2%) |
33 (80.5%) |
0.5 |
Chronic FPIES |
39 (25.8%) |
8 (19.5%) |
0.5 |
Sex ratio (male/female) (% boys) |
76/75 (50.3%) |
20/21 (48.8%) |
1.0 |
Atopic history
Personal
Paternal
Maternal
Siblings
|
52/140 (37.1%)
44/145 (30.3%)
68/145 (46.9%)
17/33 (51.5%)
|
20/37 (54.1%)
16/36 (44.4%)
19/36 (52.8%)
4/11 (36.4%)
|
0.09
0.1
0.6
0.5
|
Age at first symptoms (months) |
5.0 (3.0-8.0) |
6.0 (3.7-10.5) |
0.049 |
Main culprit food
Cow’s milk
Hen’s egg
Fish
Other foods
|
93 (61.6%)
20 (13.2%)
13 (8.6%)
25 (16.6%)
|
15 (36.6%)
9 (22.0%)
8 (19.5%)
9 (22.0%)
|
0.005
0.2
0.9
0.5
|
Minor Criteria (acute FPIES) (mean)
Recurrent vomiting after same food
Lethargy
Pallor
Emergency department visit
Diarrhea
Intravenous fluid support
Vomiting after different food
Hypotension
Hypothermia
|
3.7 per FPIES
98/112 (87.5%)
90/112 (80.4%)
71/112 (63.4%)
49/112 (43.8%)
41/112 (36.6%)
39/112 (34.8%)
25/112 (22.3%)
6/87 (6.9%)
0
|
2 per FPIES
25/33 (75.8%)
18/33 (54.5%)
6/32 (18.2%)
6/33 (18.2%)
7/33 (21.2%)
1/31 (3.2%)
3/33 (9.1%)
0/23
0
|
<0.001
0.1
0.006
<0.001
0.008
0.1
<0.001
0.1
0.3
-
|
Positive IgE |
20/142 (14.1%) |
8/38 (21.1%) |
0.3 |
Severe form |
13 (8.6%) |
0 |
0.07 |
Age at first OFC |
2.0 (1.4-2.9) |
2.3 (0.8-2.9) |
0.3 |
Age at tolerance |
2.1 (1.7-3.0) |
2.5 (1.6-2.9) |
0.7 |
Number of tolerant patients |
114 (75.5%) |
37 (90.2%) |
0.05 |