Statistical analysis
Data was analyzed by GraphPad Prism softwareⓇ (CA,
USA). The BET pharmacokinetics data are presented as median and
interquartile range. Pharmacokinetic parameters presented a normal
distribution (Shapiro-Wilk test; p-value<0.05) so they were
compared using ANOVA’s test with Tukey’s multiple comparisons test
(p-value<0.05).26,27 Correlations between
clinical features and pharmacokinetic parameters were analyzed using
Pearson’s correlation (p-value <0.05).