Statistical analysis
All of the statistical analyses were performed using the SPSS software, version 23.0 for Mac (SPSS Inc, Chicago IL, USA). The Shapiro Wilk test was used to evaluate the normality of distribution of continuous variables. Categorical variables were presented as frequencies and percentages and compared with Chi-square test or Fisher’s exact test. Normally distributed continuous variables were presented as mean \(\pm\)standard deviation (SD) and compared by the One-Way ANOVA test between the groups. The paired sample t-test was used for the comparison of normally distributed variables at the different time points in each group. The Spearmen rank-order correlation test was used to determine correlations between different variables. A p value of <0.05 was considered statistically significant.
This single-centered, prospective study was conducted in accordance with the Declaration of Helsinki, and the study protocol was approved by the Prospective Ethics Committee of X X University Faculty of Medicine (reference number: 04.06.2020-65)