Table 5. The studies about the region-based evaluation of mpMRI and PET/MRI
Study / Year
No. of Patients
Evaluated region per patient
Radiotracer
mpMRI
mpMRI
mpMRI
PET/MRI
PET/MRI
SEN (%) SPE (%) SPE (%) SEN (%) SPE (%)
Perrot et al. [16], 2014 23 8 regions 18F-Fluorocholine 60 86 86 79 70
Eiber et al. [5], 2016 53 6 regions 68Ga-PSMA 58 82 82 76 97
Lee et al. [17], 2016 31 6 regions 18F-Choline 58 58 87 73 82
18F-FDG 64 80
Hicks et al. [18], 2018 32 30 regions 68Ga-PSMA 67* 71* 71* 42* 79*
74** 88** 88** 50** 90**
Jambor et al. [19], 2018 26 12 regions 18F-FACBC 77 99 99 84 96
Park et al. [20], 2018 33 2 regions 68Ga-PSMA 53 100 100 86 88
Abbreviations. SEN: sensitivity, SPE: specificity, PSMA: Prostate specific membrane antigen, FDG: Fluorodeoxyglucose, FACBC: fluorocyclobutanecarboxylic acid * raw stringent approach ** neighbouring approach Abbreviations. SEN: sensitivity, SPE: specificity, PSMA: Prostate specific membrane antigen, FDG: Fluorodeoxyglucose, FACBC: fluorocyclobutanecarboxylic acid * raw stringent approach ** neighbouring approach Abbreviations. SEN: sensitivity, SPE: specificity, PSMA: Prostate specific membrane antigen, FDG: Fluorodeoxyglucose, FACBC: fluorocyclobutanecarboxylic acid * raw stringent approach ** neighbouring approach Abbreviations. SEN: sensitivity, SPE: specificity, PSMA: Prostate specific membrane antigen, FDG: Fluorodeoxyglucose, FACBC: fluorocyclobutanecarboxylic acid * raw stringent approach ** neighbouring approach Abbreviations. SEN: sensitivity, SPE: specificity, PSMA: Prostate specific membrane antigen, FDG: Fluorodeoxyglucose, FACBC: fluorocyclobutanecarboxylic acid * raw stringent approach ** neighbouring approach Abbreviations. SEN: sensitivity, SPE: specificity, PSMA: Prostate specific membrane antigen, FDG: Fluorodeoxyglucose, FACBC: fluorocyclobutanecarboxylic acid * raw stringent approach ** neighbouring approach Abbreviations. SEN: sensitivity, SPE: specificity, PSMA: Prostate specific membrane antigen, FDG: Fluorodeoxyglucose, FACBC: fluorocyclobutanecarboxylic acid * raw stringent approach ** neighbouring approach Abbreviations. SEN: sensitivity, SPE: specificity, PSMA: Prostate specific membrane antigen, FDG: Fluorodeoxyglucose, FACBC: fluorocyclobutanecarboxylic acid * raw stringent approach ** neighbouring approach Abbreviations. SEN: sensitivity, SPE: specificity, PSMA: Prostate specific membrane antigen, FDG: Fluorodeoxyglucose, FACBC: fluorocyclobutanecarboxylic acid * raw stringent approach ** neighbouring approach