Study / Year
|
No. of Patients
|
Evaluated region per patient |
Radiotracer
|
mpMRI
|
mpMRI
|
mpMRI
|
PET/MRI
|
PET/MRI
|
SEN (%) | SPE (%) | SPE (%) | SEN (%) | SPE (%) | ||||
Perrot et al. [16], 2014 | 23 | 8 regions | 18F-Fluorocholine | 60 | 86 | 86 | 79 | 70 |
Eiber et al. [5], 2016 | 53 | 6 regions | 68Ga-PSMA | 58 | 82 | 82 | 76 | 97 |
Lee et al. [17], 2016 | 31 | 6 regions | 18F-Choline | 58 | 58 | 87 | 73 | 82 |
18F-FDG | 64 | 80 | ||||||
Hicks et al. [18], 2018 | 32 | 30 regions | 68Ga-PSMA | 67* | 71* | 71* | 42* | 79* |
74** | 88** | 88** | 50** | 90** | ||||
Jambor et al. [19], 2018 | 26 | 12 regions | 18F-FACBC | 77 | 99 | 99 | 84 | 96 |
Park et al. [20], 2018 | 33 | 2 regions | 68Ga-PSMA | 53 | 100 | 100 | 86 | 88 |
Abbreviations. SEN: sensitivity, SPE: specificity, PSMA: Prostate specific membrane antigen, FDG: Fluorodeoxyglucose, FACBC: fluorocyclobutanecarboxylic acid * raw stringent approach ** neighbouring approach | Abbreviations. SEN: sensitivity, SPE: specificity, PSMA: Prostate specific membrane antigen, FDG: Fluorodeoxyglucose, FACBC: fluorocyclobutanecarboxylic acid * raw stringent approach ** neighbouring approach | Abbreviations. SEN: sensitivity, SPE: specificity, PSMA: Prostate specific membrane antigen, FDG: Fluorodeoxyglucose, FACBC: fluorocyclobutanecarboxylic acid * raw stringent approach ** neighbouring approach | Abbreviations. SEN: sensitivity, SPE: specificity, PSMA: Prostate specific membrane antigen, FDG: Fluorodeoxyglucose, FACBC: fluorocyclobutanecarboxylic acid * raw stringent approach ** neighbouring approach | Abbreviations. SEN: sensitivity, SPE: specificity, PSMA: Prostate specific membrane antigen, FDG: Fluorodeoxyglucose, FACBC: fluorocyclobutanecarboxylic acid * raw stringent approach ** neighbouring approach | Abbreviations. SEN: sensitivity, SPE: specificity, PSMA: Prostate specific membrane antigen, FDG: Fluorodeoxyglucose, FACBC: fluorocyclobutanecarboxylic acid * raw stringent approach ** neighbouring approach | Abbreviations. SEN: sensitivity, SPE: specificity, PSMA: Prostate specific membrane antigen, FDG: Fluorodeoxyglucose, FACBC: fluorocyclobutanecarboxylic acid * raw stringent approach ** neighbouring approach | Abbreviations. SEN: sensitivity, SPE: specificity, PSMA: Prostate specific membrane antigen, FDG: Fluorodeoxyglucose, FACBC: fluorocyclobutanecarboxylic acid * raw stringent approach ** neighbouring approach | Abbreviations. SEN: sensitivity, SPE: specificity, PSMA: Prostate specific membrane antigen, FDG: Fluorodeoxyglucose, FACBC: fluorocyclobutanecarboxylic acid * raw stringent approach ** neighbouring approach |