Introduction
Blue rubber bleb nevus syndrome (BRBNS) is a rare congenital disease
characterized by multifocal venous malformations, mostly involved in
skin and gastrointestinal (GI) tract [1]. The
positon of venous malformations can run through the GI tract, and the
small intestine is the most common lesion location, which cause chronic
occult bleeding and iron deficient anemia (IDA). The diagnosis of BRBNS
is developed when typical malformations of venous appears[2], but some cases had underground lesions
leading to long term misdiagnosis. Here, we report a case misdiagnosed
with refractory IDA for 12 years, who ultimately display the underlying
disease of BRBNs uncovered by GI endoscopy and capsule endoscopy.