Conclusion
Varenicline may have a positive effect on smoking cessation in people with alcohol dependence. However, Naltrexone, Topiramate, and Bupropion seem to have no clear effect on increasing smoking abstinence among drinkers. The small number of studies and the low certainty of evidence indicate that caution is required in interpreting the results.
Keywords:Smoking Cessation, Alcohol Dependence, Pharmacotherapies, Systematic Review and Meta-analysis