Fig. 2. Electric-induced (A)
RD and (B) TBF of 5dpf panx1a+/+ and
panx1a-/- zebrafish larvae exposed to 250µM 6-OHDA for
0 and 72hrs. (15 larvae per experimental condition in three independent
trials, N = 45). (C) The RT-qPCR data showing 6-OHDA-induced change in
tyrosine hydroxylase (TH) expression of larvae treated with 250µM 6-OHDA
for 0 and 72hrs. Dotted line at Y=1 represents the TH expression level
in panx1a+/+ control group. Each value represents
Mean \(\pm\) SEM of three independent experiments (N=150/group).
All data were compared with the panx1a+/+ control
group. **: p<0.01, ***: p<0.001.