Conclusion:
This case highlights the co-occurrence of rheumatoid arthritis with GFAP associated astrocytopathy, and expands on the previously reported cases with similar association. This might also suggest a common immune pathogenesis.
Abbreviations:
GFAP: Autoimmune glial fibrillary acidic protein
CNS: central nervous system
CSF: cerebrospinal fluid
IgG: immunoglobulin-G
AQP4: aquaporin-4
NMDAR: N-methyl-D-aspartate receptor