Parameter |
Base |
RSE (%) |
rs2295890 |
RSE (%) |
p-value |
CL (L/h/m2) |
6.87 |
4.8 |
7.17 |
5.2 |
|
β: CL*
|
|
|
-0.29 |
43.3 |
0.02 |
V (L/m2) |
18.74 |
4.5 |
18.55 |
4.7 |
|
Q (L/h/m2) |
14.21 |
0.2 |
14.46 |
0.2 |
|
V2 (L/m2) |
25.67 |
1.3 |
25.99 |
1.8 |
|
σ additive (µM) |
0.06 |
20.0 |
0.06 |
15.4 |
|
σ prop
CV%)
|
0.10
|
4.1
|
0.10
|
6.3
|
|
-2 Log-likelihoodb
|
1750.2 |
|
1739.5 |
|
0.001 |
IIV |
(CV%) |
RSE (%) |
(CV%) |
RSE (%) |
|
CL |
0.57 |
6.6 |
0.56 |
6.8 |
|
V |
0.33 |
21.2 |
0.34 |
19.8 |
|
Q |
0.70 |
11.8 |
0.71 |
9.1 |
|
V2
|
0.40 |
12.8 |
0.44 |
13.5 |
|