a Covariate model: θ*exp(β*covariate). rs2295890: 0=WT, 1=HET/MUT.
b p-value represents the significance of the change in the -2 log-likelihood (based on theχ2 test) relative to base model
Abbreviations: RSE, relative standard error; CL, clearance; V, volume of distribution; Q, intercompartmental clearance; CV%, coefficient of variation; IIV, interindividual variation.