2. METHODS
This study is a cross sectional study conducted of collected data on
patients of all age groups, this study was performed on 340 suspected
COVID-19 patients, who presented to Chamran Hospital, Shiraz University
of Medical Sciences Shiraz, Iran from 20 February to 31 August 2020 and
in this study after obtaining permission from the ethics committee and
approving the research plan, the clinical and laboratory findings of
covid-19 patients were extracted from the electronic medical records of
the patients. Information each patient including the evaluation of lungs
and kidney involvement in CT scan and sonography and their relationship
with laboratory indicator including biochemical and hematological
factors for the severity and prognosis of Covid 19 disease was
investigated by a trained team of physicians. The data about clinical
symptoms, medicine treatment and laboratory parameters were collected by
patient record, and based on the doctor’s diagnosis and CT scan reports
and PCR test of throat Secretions. Nasal and pharyngeal swab samples and
sputum were obtained from patients on admission. We retrospectively
analyzed and evaluated the epidemiological history, comorbidity, vital
signs, and symptoms obtained from electronic medical records. The data
collection forms were reviewed independently by two experienced
physicians, and the severity of the disease is determined by the need
for ICU, sepsis, involvement of the lungs and other organs, intubation,
ventilation, death. The information of each case was completed using a
data collection form based on the records recorded in the patient file
and the examination of radiological photographs, and a sample of the
data collection form was attached. Other variables studied include the
need for ICU hospitalization and the time of hospitalization from the
onset of symptoms to hospitalization and the need for intubation and
ventilation. Problems include ARDS, Renal Injury, Septic Shock and
Ventilator Associated Injury. In this study, CT scan reports are
examined and the consistency of patients’ deterioration based on these
reports with the patient’s fate in the case is examined. Inclusion
criteria included, all positive coronavirus patients referred to chamran
Hospital, who need to be hospitalized. Exclusion criteria included,
deaths before admission to the hospital and positive coronavirus
patients or those who for some reason refused to visit the hospital.
This project has been approved by the research ethics committee with the
code of IR.SUMS.REC. 1399.S605 and project number of 99-10-24-13415
by Shiraz University of Medical Sciences in Shiraz, Iran.