CVID QoL scores are presented as median (min-max) and mean (SD) in Turkish study group, mean (SD) in Italian and Norwegian group. Abbreviations; CVID: common variable immunodeficiency, SD: standard deviation, SCIG: subcutaneous immunoglobulin, IVIG: intravenous immunoglobulin, NA: not available

Figure legends

Figure 1. Flowchart of the stages of cross-cultural adaptation and content validation of CVID QoL

Abbreviations; T1-T2: first and second translations from Italian to Turkish, CVID: common variable immune deficiency

Figure 2. Number of infections and CVID QoL, EF, RF, GSS scores. Patients were divided according to the number of infections within 3 months (A ) and within 12 months (B ). P values of CVID QoL global, EF, RF scores within 3 months between 0-1 infection and >1 infection were 0.038, 0.045, 0.028 respectively. P values of CVID QoL global, EF, RF scores within 12 months between 0-2 infections, 3-6 infections and >6 infections were p>0.05.

Abbreviations: CVID, common variable immune deficiency; EF, emotional functioning; RF, relational functioning; GSS, gastrointestinal and skin symptoms; QoL, quality of life.