Correlation analysis of FMD and other parameters
In the correlation analysis of FMD with biomarkers, there was a significant negative correlation between FMD and VEGF (p=0.004, r=-0,402), ET-1 (p=0.01, r=-0,363), endocan (p=0.006, r=-0,390), systolic (p=0.009, r=-0.368) and diastolic (p=0.003, r=-0.419) blood pressure in the patients (Supplement Figure-1, Table-4). FMD values did not differ according to gender, smoking habits, family history of coronary artery diseases, history of anaphylaxis and other clinical features including c-kit positivity, serum baseline tryptase levels and the presence of hepatosplenomegaly, skin or bone lesions (p>0.05).