Results of biomarkers
Among endocan, VEGF, ET-1, TNF-α, IL-6, hsCRP and ESR, the median value
of VEGF was significantly higher in the patients than HCs (p=0.001)
while there were no significant differences between groups regarding
other biomarkers (Table 2).
The Kruskal Wallis test revealed that the median (min-max) VEGF levels
were different between four groups including HCs [46.64 (11.09-99.86)
pg/mL], group-1 [47.56 (40.47-225.53) pg/mL], group-2 [74.01
(32.46-295.29) pg/mL] and group-3 [104.17 (49.25-248.46) pg/mL]
(p:0.002) (Table:3). Post-hoc analysis showed that both group-2 and
group-3 revealed higher VEGF levels than HCs (p=0.01, for each) and
group-3 had the highest values.