What’s already known about this topic?
1. Female sexual dysfunction (FSD) is a considerably underestimated condition, affects almost half of premenopausal sexually active women.
2. Various mediators, including dopamine, norepinephrine, melanocortin, oxytocin, testosterone, estradiol, progesterone, vasoactive intestinal polypeptide, nitric oxide, calcitonin gene-related peptide and neuropeptide-Y play a role in female sexual function.
3. Many factors may contribute to FSD, including obesity, diabetes mellitus, smoking, hyperlipidemia, heart diseases, liver failure, alcoholism, depression, drug abuse or medications.