Differences between SLE patients and healthy subjects
We observed a significant increase in the frequency of expression of cell activation and exhaustion markers in both the CD4+ and the CD8+ compartment between the SLE patients and HS group. The T cell subpopulations in SLE patients presented an increase in the frequency of PD-1, CD57, EOMES, and exhausted and activated populations when compared with the HS group. Table 4 and Figure 2 shows all the populations that were identified as differentially expressed between groups.