T cells populations
Healthy Subjects Active SLE PR-SLE p
N = 29 N = 15 N = 15
CD3+ % 60.8 (56.2 – 69.2) 68.0 (53.7 – 78.2) 67.7 (61.4 – 74.4) 0.23
CD3+CD4+ % 35.4 (33.5 – 43.1) 39.4 (25.8 – 46.7) 39.0 (31.4 – 46.6) 0.92
Naïve (CD45RA+CD197+) % 27.9 (19.4 – 33.1) 23.2 (7.98 – 40.2) 19.3 (11.3 – 32.5) 0.28
CM (CD45RA-CD197+) % 25.3 (16.1 – 34.6) 26.5 (16.2 – 44.5) 40.7 (22.1 – 45.3) 0.04††
EM (CD45RA-CD197-) % 40.9 (31.2 – 53.0) 39.6 (36.2 – 62.7) 39.9 (26.9 – 47.5) 0.66
TEMRA (CD45RA+CD197-) % 2.26 (1.40 – 4.26) 2.63 (0.78 – 4.09) 0.92 (0.66 – 2.14) 0.11
CD25+ % 9.81 (5.68 – 14.8) 11.2 (8.27 – 22.4) 15.3 (9.13 – 32.0) 0.09
CD127low % 5.19 (4.20 – 6.83) 5.42 (4.96 – 6.85) 5.74 (4.29 – 9.15) 0.88
CD25+CD127lowFOXP3+ % 1.16 (0.38 – 2.13) 0.54 (0.23 – 1.52) 1.13 (0.25 – 1.79) 0.37
CD3+CD8+ % 18.4 (14.8 – 21.9) 18.9 (13.4 – 22.3) 19.0 (12.5 – 25.2) 0.95
Naïve (CD45RA+CD197+) % 21.5 (14.2 – 25.5) 24.9 (15.3 – 51.7) 14.7 (8.59 – 24.4) 0.04
CM (CD45RA-CD197+) % 3.13 (1.71 – 5.67) 2.88 (1.42 – 6.45) 8.73 (3.74 – 10.3) 0.01‡, ††
EM(CD45RA-CD197-) % 41.4 (36.1 – 45.2) 27.8 (18.0 – 38.8) 38.0 (28.8 – 50.0) 0.04*
TEMRA (CD45RA+CD197-) % 33.8 (24.0 – 38.8) 34.1 (19.0 – 45.0) 35.2 (24.4 – 46.6) 0.95
Results are shown in Median with Interquartile Range, and Kruskal Wallis test was used to perform comparisons between groups. Mann Whitney U test was performed to compare between two groups as a post Hoc test and are represented by the following symbols. * Healthy Subjects vs Act SLE. * p < 0.05. ** p < 0.01. *** p < 0.001. † Healthy Subjects vs PR-SLE. † p < 0.05. †† p < 0.01. ††† p < 0.001. ‡ Act-SLE vs PR-SLE. ‡ p < 0.05. ‡‡ p < 0.01. ‡‡‡ p < 0.001. Results are shown in Median with Interquartile Range, and Kruskal Wallis test was used to perform comparisons between groups. Mann Whitney U test was performed to compare between two groups as a post Hoc test and are represented by the following symbols. * Healthy Subjects vs Act SLE. * p < 0.05. ** p < 0.01. *** p < 0.001. † Healthy Subjects vs PR-SLE. † p < 0.05. †† p < 0.01. ††† p < 0.001. ‡ Act-SLE vs PR-SLE. ‡ p < 0.05. ‡‡ p < 0.01. ‡‡‡ p < 0.001. Results are shown in Median with Interquartile Range, and Kruskal Wallis test was used to perform comparisons between groups. Mann Whitney U test was performed to compare between two groups as a post Hoc test and are represented by the following symbols. * Healthy Subjects vs Act SLE. * p < 0.05. ** p < 0.01. *** p < 0.001. † Healthy Subjects vs PR-SLE. † p < 0.05. †† p < 0.01. ††† p < 0.001. ‡ Act-SLE vs PR-SLE. ‡ p < 0.05. ‡‡ p < 0.01. ‡‡‡ p < 0.001. Results are shown in Median with Interquartile Range, and Kruskal Wallis test was used to perform comparisons between groups. Mann Whitney U test was performed to compare between two groups as a post Hoc test and are represented by the following symbols. * Healthy Subjects vs Act SLE. * p < 0.05. ** p < 0.01. *** p < 0.001. † Healthy Subjects vs PR-SLE. † p < 0.05. †† p < 0.01. ††† p < 0.001. ‡ Act-SLE vs PR-SLE. ‡ p < 0.05. ‡‡ p < 0.01. ‡‡‡ p < 0.001. Results are shown in Median with Interquartile Range, and Kruskal Wallis test was used to perform comparisons between groups. Mann Whitney U test was performed to compare between two groups as a post Hoc test and are represented by the following symbols. * Healthy Subjects vs Act SLE. * p < 0.05. ** p < 0.01. *** p < 0.001. † Healthy Subjects vs PR-SLE. † p < 0.05. †† p < 0.01. ††† p < 0.001. ‡ Act-SLE vs PR-SLE. ‡ p < 0.05. ‡‡ p < 0.01. ‡‡‡ p < 0.001. Results are shown in Median with Interquartile Range, and Kruskal Wallis test was used to perform comparisons between groups. Mann Whitney U test was performed to compare between two groups as a post Hoc test and are represented by the following symbols. * Healthy Subjects vs Act SLE. * p < 0.05. ** p < 0.01. *** p < 0.001. † Healthy Subjects vs PR-SLE. † p < 0.05. †† p < 0.01. ††† p < 0.001. ‡ Act-SLE vs PR-SLE. ‡ p < 0.05. ‡‡ p < 0.01. ‡‡‡ p < 0.001.