Statistical Analysis
Analyses were performed using SPSS Statistics v21.0 (IBM, Chicago, IL,
USA). Not-normally distributed continuous data were expressed as median
and interquartile ranges (IQR). Group comparisons were carried out using
Mann–Whitney U-test or ANOVA as appropriate for the continuous, and the
chi-square test or Fisher test for categorical variables. The
correlation coefficients between clinical manifestations and other
clinical variables were determined using Spearman‘s rank correlation or
Pearsons coefficient. A P level <0.05 was considered
significant.