Conclusion
In conclusion, we demonstrated a significant and independent association
between serum periostin and asthma severity in children. Our findings
highlight the diagnostic role of periostin in identifying children with
severe asthma. Further studies are needed to better demonstrate the role
of periostin in the asthma pathogenesis and clinical utility for the
physicians dealing with children with asthma.
Acknowledgements: We are extremely grateful to all the patients
and their families who took part in this study. We would also like to
acknowledge the hard work and dedication of the study team, which
includes physicians, laboratory technicians and nurses.