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\title{Neuroimaging findings and risk factors for neurologic toxicity after
hematopoietic stem cell transplant in children}



\author[1]{Elizabeth Duke}%
\author[2]{Leslie Lehman}%
\author[3]{Nicole Ullrich}%
\affil[1]{Children's National Health System}%
\affil[2]{Dana-Farber/Boston Children's Cancer and Blood Disorders Center}%
\affil[3]{Children's Hospital Boston}%


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  \date{May 18, 2024}


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\begin{abstract}
Neurologic complications after hematopoietic stem cell transplant (HSCT)
in children are poorly described, but may contribute to morbidity and
mortality. We retrospectively reviewed 261 patients who underwent
allogeneic or autologous HSCT, of whom 57 had brain magnetic resonance
imaging (MRI) post-transplant, and subsequently identified indications
for imaging and determined correlation of findings with neurologic
symptoms. Approximately half of imaging studies were done to investigate
new neurologic symptoms; of those, 1/3 had acute findings on MRI that
correlated with symptoms. Imaging done in patients at risk for
neurologic processes but without active neurologic symptoms did not
demonstrate acute or actionable findings.%
\end{abstract}%



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