Effect of activation mapping on acute success and VT recurrences
Complete activation mapping was performed in 50 patients (35.2%, 50/142
inducible patients) and was significantly more frequently among patients
with only 1 VT morphology induced compared with patients with
>1 VT morphology induced (49.1% vs. 27%, p=0.011). In the
remaining 110 patients substrate guide ablation ± pacemapping was used
as ablation strategy. Acute success was comparable between patients with
complete activation mapping and patients without activation mapping
(81.2% vs 70.7%, respectively, p=0.22).
However, survival free of VT recurrence was significantly higher when
activation mapping had been performed during the procedure (76% vs
63%, Log-rank p=0.028)(figure 2B). Of note, in patients with only 1 VT
induced (group 2) and complete activation mapping (26 group 2 patients)
only 4 VT recurrences occurred during follow-up in comparison with 44 VT
recurrences in 115 patients with either >1VT induced or
impossibility of activation mapping (84.6% survival free of VT
recurrence vs. 63.8%, respectively, Log-rank p=0.002)(Supplementary
material).