Effect of activation mapping on acute success and VT recurrences
Complete activation mapping was performed in 50 patients (35.2%, 50/142 inducible patients) and was significantly more frequently among patients with only 1 VT morphology induced compared with patients with >1 VT morphology induced (49.1% vs. 27%, p=0.011). In the remaining 110 patients substrate guide ablation ± pacemapping was used as ablation strategy. Acute success was comparable between patients with complete activation mapping and patients without activation mapping (81.2% vs 70.7%, respectively, p=0.22).
However, survival free of VT recurrence was significantly higher when activation mapping had been performed during the procedure (76% vs 63%, Log-rank p=0.028)(figure 2B). Of note, in patients with only 1 VT induced (group 2) and complete activation mapping (26 group 2 patients) only 4 VT recurrences occurred during follow-up in comparison with 44 VT recurrences in 115 patients with either >1VT induced or impossibility of activation mapping (84.6% survival free of VT recurrence vs. 63.8%, respectively, Log-rank p=0.002)(Supplementary material).