3.1. Patient and control finding
Patients with CoA (n = 42) and
healthy volunteers (n = 39) were
included in this study. The mean age of the patients was 5.8 ± 4.5 years
and there were 23 boys and 19 girls included in the study. No
significant differences between CoA and healthy volunteers were detected
with regard to sex, age, body mass index, or heart rate (p = 0.88, p =
0.59, p = 0.26, p = 0.20). Clinical and demographic characteristics of
the patients are summarized in Table 1. Among the CoA group, four
patients had ventricular septal defects, one had an atrioventricular
septal defect, and one had partial anomalous pulmonary venous return. In
addition, two patients had mild aortic stenosis.
In CoA group was significantly higher the mean systolic blood pressure
in comparison to the control group (109.41±16.20 mmHg and
97.23±10.10mmHg, respectively; p < .001). Arterial
hypertension was found in 14 (33.3%) children from the hypertensive CoA
group, the remaining 22 children (52.3%) in the CoA group were
normotensive. Of the 27 patients that underwent surgery, five patients
underwent catheter angiography and 10 patients underwent both surgical
and catheter angiography. The median time from CoA repair to the present
study was 3.74 ±2.3 years. The operating age of the patients was 7.4 ±
21 months. Repairs were performed by subclavian flap in 17 patients and
by end-to-end anastomosis in 10 patients. A bicuspid aortic valve was
present in 20 (47.6%) patients in the CoA group.